argNorm is a tool to normalize antibiotic resistance genes (ARGs) by mapping them to the antibiotic resistance ontology (ARO) by CARD. It also provides drug categorization of drugs that antibiotic resistance genes confer resistance to.
Different ARG annotation tools report results using their own naming schemes, which makes it hard to compare or combine outputs. argNorm solves this by normalizing the outputs of many widely-used tools — including NCBI AMRFinderPlus, CARD/RGI, ResFinder, ARG-ANNOT, DeepARG, MEGARes, SARG, and GROOT — to a common ontology, and works directly with hAMRonization-formatted input.
The current version is argNorm 1.1.0 (released June 2025), which improves NCBI mappings (particularly for hAMRonized data) and fixes a number of edge cases.
argNorm is available on PyPI and bioconda:
pip install argnorm
# or
conda install -c bioconda argnorm
Copyright (c) 2018–2026. Luis Pedro Coelho and other group members. All rights reserved.